HiFive: a tool suite for easy and efficient HiC and 5C data analysis
نویسندگان
چکیده
منابع مشابه
HiFive: A normalization approach for higher-resolution HiC and 5C chromosome conformation data analysis
While sequencing-based proximity assays have established many megabase-scale features of chromosome organization, experimental noise and biases have left finer-scale organization poorly understood. We developed HiFive, an empirically-driven probabilistic modeling approach for normalizing and analyzing HiC and 5C data. HiFive allows reconstruction of chromatin structural features at higher resol...
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ژورنال
عنوان ژورنال: Genome Biology
سال: 2015
ISSN: 1474-760X
DOI: 10.1186/s13059-015-0806-y